Lab Members
Current Laboratory Members
.
Principal Investigator
Adele Guerin
Senior Research Assistant
Yuzhen Li, Ph.D.
Instructor
Dorcas Oladapo
Research Assistant II
M谷lanie Prodhomme, Ph.D.
Postdoctoral Fellow
Zeba Siddiqui, Ph.D.
Postdoctoral Fellow
Former Trainees and Laboratory Members
The predoctoral and postdoctoral trainees listed below were supported by competitive grants to come to my laboratory. These grants include: the Human Frontiers Science Program, EMBO, Japan Society for Promotion of Science, Imperial Cancer Research Fund, the University of Pittsburgh Competitive Medical Research Fund, and NRSA Ruth Kirschstein funding from the NIH.
Predoctoral Trainees
| Name, Prior Degree, Years in Lab |
Institution | Research Project | Current Position |
|---|---|---|---|
| Sofia Ara迆jo, B.S. 1995每1999 |
ICRF | Interactions and function of nucleotide excision repair complexes | Associate Professor, Faculty of Biology, University of Barcelona, Spain |
| Dawn Batty, B.S. 1995每1999 |
ICRF | The XPC-RAD23B complex and nucleotide excision repair of DNA | Principal Medical Writer, Aspire Scientific, Buxton, UK |
| Maureen Biggerstaff-Bowles, B.S., M.S. 1995每2002 |
ICRF | DNA repair defects in ERCC1, ERCC4 and XPF mutants | Senior Research Officer (ret), Francis Crick Institute, UK |
| Dawn Coverley, B.S. 1987 -1991 |
ICRF | Proteins involved in human DNA excision repair | Professor, University of York, UK; Chief Scientific Officer, Cizzle Biotech |
| Gregory Gan, B.S. 2003每2007 |
University of Pittsburgh | Function of Rev3L | Assistant Professor, University of Kansas Medical Center |
| Mandira Manandhar, B.S., M.S. 2010每2016 | UT MD Anderson | XPA and DNA crosslink repair | Research Scientist, UT MD Anderson |
| Jonathan Moggs, B.S. 1993每1997 |
ICRF | Incision mechanism during human nucleotide excision repair | Head, Mechanistic and Predictive Safety, Novartis Institute for Biomedical Research, Basel, Switzerland |
| Anne (O'Donovan) Jones, B.S. 1991每1994 |
ICRF | The xeroderma pigmentosum group G DNA repair protein | President and CEO, G-CON Manufacturing, Inc., College Station, Texas |
| Mahmud Shivji, B.S 1991每1996 |
ICRF | Nucleotide excision repair of DNA: Dissection and reconstitution in vitro | Group Research Manager (ret), Hutchinson/MRC Research Center, Cambridge, UK |
| Matt Yousefzadeh, B.S. 2009每2015 |
UT MD Anderson | DNA polymerase POLQ and cellular defense against DNA damage | Assistant Professor, Columbia University Irving Medical Center |
| Sara Martin, B.S. 2015每2020 |
UT MD Anderson | DNA polymerase zeta and innate immune responses | Postdoctoral Fellow, Tufts University, Medford MA |
Postdoctoral Trainees
| Name, Prior Degree, Years in Lab |
Institution | Project | Current Position |
|---|---|---|---|
Abdelilah Aboussekhra, Ph.D. |
ICRF | Reconstitution of human NER with purified proteins | Principal Scientist and Chair, Department of Molecular Oncology, King Faisal Specialist Hospital and Research Center, Saudi Arabia |
| Rafael Ariza, Ph.D. 1993每1996 |
ICRF | Cloning of the human XPF gene | Professor, University of C車rdoba, Spain |
| Hiroshi Asahina, Ph.D. 1997每1999 |
ICRF | The swi10-rad16 nuclease | Technical Staff, Sales, Cellular Dynamics International, Tokyo, Japan |
| Denisse Carvajal Maldonado, Ph.D. 2019每2023 |
UT MD Anderson | DNA polymerase theta mediated repair | Scientist I, ORIC Pharmaceuticals, South San Francisco |
| Elizabeth Evans, Ph.D. 1995每1997 |
ICRF | The pre-incision opening reaction during human NER | Director, Liberal Arts Consortium for Online Learning, Drexel University, Philadelphia |
| Guido Frosina, Ph.D. 1988每1989 |
ICRF | Transcription-coupled repair | Mutagenesis & Cancer Prevention Unit, IRCCS Ospedale Policlinico San Martino, Genova, Italy |
| Pierre-Henri Gaillard, Ph.D. 1997每2000 |
ICRF | The ERCC1-XPF nuclease | Group Leader, CNRS, Cancer Research Center of Marseille, France |
| Daniela Gunz, Ph.D. 1997每1999 |
ICRF | DNA repair functions of XPG protein | Director of Research Partnerships, Healthbank Innovation AG; Founder & Managing Partner, Hermelin GmbH, Z邦rich, Switzerland |
| Johan Hansson, M.D. 1987每1990 |
ICRF | Nucleotide excision repair of cisplatin-DNA adducts | Professor, Karolinska Institutet, Stockholm, Sweden |
| Christopher Jones, Ph.D. 1989每1993 |
ICRF & University of Pittsburgh |
Human XPA protein | VP, Scientific at ApotheCom, : A MEDiSTRAVA Company (Medical Division of Huntsworth) |
| Stephen Keyse, Ph.D. 1989每1991 | ICRF | Protein kinase phosphatases and nucleotide excision repair | Professor Emeritus, School of Medicine, University of Dundee, UK |
| Nayun Kim, Ph.D. 2000每2003 |
ICRF & University of Pittsburgh |
A novel human DNA polymerase | Associate Professor, Department of Microbiology and Molecular Genetics, University of Texas Health Science Center at Houston |
| Beate K?berle, Ph.D. 1998每2006 |
ICRF & University of Pittsburgh |
Cisplatin sensitivity and nucleotide excision repair | Institute of Applied Biosciences, Karlsruhe Institute of Technology (KIT), Germany |
| Isao Kuraoka, Ph.D. 1996每2001 |
ICRF | Repair of DNA crosslinks and cyclopurine adducts | Associate Professor, Department of Chemistry, Fukuoka University, Japan |
| Sabine Lange, Ph.D. 2009每2014 |
UT MD Anderson | The impact of DNA damage responses on energy metabolism and proteostasis | Chief Toxicologist, Toxicology, Risk Assessment, and Research Division, Texas Commission on Environmental Quality (TCEQ), Austin, TX |
| Frederica Marini, Ph.D. 1998每2008 |
ICRF & University of Pittsburgh |
New DNA polymerase and helicases for crosslink repair | Research Group Leader, Department of Biosciences, University of Milan, Italy |
| Mineaki Seki, Ph.D. 2000每2008 |
ICRF & University of Pittsburgh |
Function of DNA polymerase Q | Associate Professor, Niigata University of Pharmacy and Applied Sciences, Japan |
| David Szymkowski, Ph.D. 1989每1993 |
ICRF | Repair of single, specific DNA lesions | Vice President, Cell Biology, Xencor, Monrovia, CA |
| Kei-ichi Takata, Ph.D. 2004每2009 |
University of Pittsburgh and UT MD Anderson | Function of DNA polymerase N and DNA helicase Q | Section Head, Institute for Basic Science, Center for Genomic Integrity, Ulsan National Institute of Science and Technology, S. Korea |
| Junya Tomida, Ph.D. 2011每2013 | UT MD Anderson | DNA double-strand break repair | Assistant Professor, University of North Carolina at Charlotte, Department of Biological Sciences |
| Birgitte Wittschieben, Ph.D. 2001每2007 |
University of Pittsburgh |
Recognition and repair of DNA lesions in chromatin | Vice President R&D Global Assay Development, Chr. Hansen Holding A/S, Copenhagen, Denmark |
| John Wittschieben, Ph.D. 1997每2008 |
ICRF & University of Pittsburgh |
Function of the mouse Rev3l gene | Senior Executive Officer, Technical University of Denmark, Copenhagen, Denmark |
Sabbatical Visitors
| Name and Years in Lab |
Host Institution | Position at Home Institution |
|---|---|---|
| Lawrence Grossman, Ph.D. 1989 |
ICRF | Professor, Department of Biochemistry, Johns Hopkins School of Public Health, Baltimore, USA |
| Graciela Spivak, Ph.D. 1994 |
ICRF | Research Associate, Stanford University, USA |
| Juhani Vilpo, M.D. 1994每1995 |
ICRF | Professor, Haematology, Tampere University Medical School, Finland |
| Chikahide Masutani, Ph.D. 2003 |
University of Pittsburgh | Professor Nagoya University, Japan |
| Stuart Clarkson, Ph.D. 2005 |
University of Pittsburgh | Professor, University of Geneva Medical School, Switzerland |
Other Members
| Name, Prior Degree, Years in Lab |
Institution | Current Position |
|---|---|---|
| Karen Boulware, B.S., M.B.A. 2008每2017 |
University of Pittsburgh/UT MD Anderson | VWR International, Lubbock, Texas |
| Vaishali Patil, B.S. 2001每2008 |
University of Pittsburgh | Retired |
| K. Leslie Powell, B.S. 2012每2014 |
UT MD Anderson | Retired |
| Shelley Reh, B.S., M.S. 2010每2017 |
UT MD Anderson | Proofreader/Editor ProofreadingServices.com |
| Vera Roginskaya, B.S. 2001每2008 |
University of Pittsburgh | University of Pittsburgh |
| David Trono, B.S. 2010每2014 |
UT MD Anderson | Retired |
| Megan Lowery, B.S. 2012每2021 |
UT MD Anderson | Retired |
| Mark Returan, B.S. 2022每2025 |
UT MD Anderson | Graduate Student at UT MD Anderson UTHealth Houston Graduate School of Biomedical Sciences |
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Research Areas
Find out about the four types of research taking place at UT?MD Anderson.