Metabolomics Facility Publications

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Publications

Year	Title	Journal	Authors (First, Last)	Services
2023	Vitamin B2 enables regulation of fasting glucose availability	eLife	P. Masschelin; S. Hartig	Custom Method
2023	Dimeric p53 Mutant Elicits Unique Tumor-Suppressive Activities through an Altered Metabolic Program	Cancer Discovery	J. Gencel-Augusto; G. Lozano	Lipidomics
2023	Targeting Glutamine Metabolism with a Novel Na+/K+-ATPase Inhibitor RX108 in Hepatocellular Carcinoma	Molecular Cancer Therapeutics	D. Wei; P. Yang	Lipidomics
2023	Mitochondrial structure and function adaptation in residual triple negative breast cancer cells surviving chemotherapy treatment	Oncogene	M. Baek; G. Echeverria	IC-MS, Stable Isotope Tracing, Seahorse
2023	Interfering with lipid metabolism through targeting CES1 sensitizes hepatocellular carcinoma for chemotherapy	JCI Insight	G. Li; K. Sun	Lipidomics, Fatty Acids Medium- and Long-Chain
2022	Mucus-degrading Bacteroides link carbapenems to aggravated graft-versus-host disease	Cell	E. Hayase; R. Jenq	IC-MS, SCFAs, Microbiome, Custom Method
2022	Pathogenesis of Tobacco-Associated Lung Adenocarcinoma Is Closely Coupled with Changes in the Gut and Lung Microbiomes	International Journal of Molecular Sciences	C. Finnicum; H. Kadara	IC-MS, SCFAs, Microbiome
2022	Tumoral microenvironment prevents de novo asparagine biosynthesis in B cell lymphoma, regardless of ASNS expression	Science Advances	M. Grima-Reyes; J. Chiche	Custom Method, Stable Isotope Tracing
2022	Calcium/calmodulin-dependent protein kinase kinase 2 regulates hepatic fuel metabolism	Molecular Metabolism	B. Stork; B. York	Stable Isotope Tracing, Seahorse
2022	Inhibition of mitochondrial complex I reverses NOTCH1-driven metabolic reprogramming in T-cell acute lymphoblastic leukemia	Nature Communications	N. Baran; M. Konopleva	IC-MS, Seahorse
2022	ATF4 Protects the Heart From Failure by Antagonizing Oxidative Stress	Circulation Research	X. Wang; Z. Wang	GSH, NADH/NADPH
2022	Adipose tissue-specific ablation of Ces1d causes metabolic dysregulation in mice	Life Science Alliance	G. Li; K. Sun	Lipidomics, Fatty Acids Medium- and Long-Chain
2022	Regulation of growth, invasion and metabolism of breast ductal carcinoma through CCL2/CCR2 signaling interactions with MET receptor tyrosine kinases	Neoplasia	D. Acevedo; N. Cheng	IC-MS, Seahorse
2022	Combined inhibition of HMGCoA reductase and mitochondrial complex I induces tumor regression of BRAF inhibitor-resistant melanomas	Cancer and Metabolism	E. de Groot; Y. Gopal	IC-MS, Amino Acids, Stable Isotope Tracing, Seahorse
2022	SRGN-Triggered Aggressive and Immunosuppressive Phenotype in a Subset of TTF-1-Negative Lung Adenocarcinomas	Journal of the National Cancer Institute	I. Tanaka; A. Taguchi	Custom Method
2021	USP21 deubiquitinase elevates macropinocytosis to enable oncogenic KRAS bypass in pancreatic cancer	Genes and Development	P. Hou; R. DePinho	Custom Method
2021	Circulating Fatty Acids Associated with Advanced Liver Fibrosis and Hepatocellular Carcinoma in South Texas Hispanics	Cancer Epidemiology, Biomarkers, and Prevention	J. Jiao; L. Beretta	Fatty Acids Medium- and Long-Chain
2021	Lipidomic Profiles of Plasma Exosomes Identify Candidate Biomarkers for Early Detection of Hepatocellular Carcinoma in Patients with Cirrhosis	Cancer Prevention Research	J. Sanchez; L. Beretta	Lipidomics
2021	Targeting MYC-enhanced glycolysis for the treatment of small cell lung cancer	Cancer and Metabolism	K. Cargill; L. Byers	Seahorse
2021	Compound NSC84167 selectively targets NRF2-activated pancreatic cancer by inhibiting asparagine synthesis pathway	Cell Death and Disease	B. Dai; J. Fleming	Amino Acids
2021	PGC1�� is required for the renoprotective effect of lncRNA Tug1 in vivo and links Tug1 with urea cycle metabolites	Cell Reports	L. Li; F. Danesh	IC-MS, HILIC-MS, Lipidomics, Amino Acids
2021	PKM1 Exerts Critical Roles in Cardiac Remodeling Under Pressure Overload in the Heart	Circulation	Q. Li; Z. Wang	IC-MS, Seahorse
2021	Choline kinase alpha 2 acts as a protein kinase to promote lipolysis of lipid droplets	Molecular Cell	R. Liu; Z. Lu	IC-MS
2021	Medium-Chain Acyl-CoA Dehydrogenase Protects Mitochondria from Lipid Peroxidation in Glioblastoma	Cancer Discovery	F. Puca; G. Draetta	Lipidomics, CoAs, Stable Isotope Tracing
2021	Development of a rational strategy for integration of lactate dehydrogenase A suppression into therapeutic algorithms for head and neck cancer	British Journal of Cancer	Y. Chen; S. Lai	IC-MS

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