
Zhao Laboratory
Di Zhao, Ph.D.
Principal Investigator
- Departments, Labs and Institutes
- Labs
- Di Zhao Laboratory
Areas of Research
- Prostate Cancer
- Genetics
- Tumor Microenvironment
- Immunotherapy
- Mouse Model Development
Over the past decade, large-scale cancer genome studies have uncovered emerging genetic alterations in malignancies. The Zhao Laboratory in the Experimental Radiation Oncology department focuses on prostate cancer biology and genetics, with a special interest in understanding crosstalk between cancer cells and immune components in the tumor microenvironment and metastatic niche.
Recent Publications
Chen F, Li H, Wang Y, Tang X, Lin K, Li Q, Meng C, Shi W, Leo J, Liang X, Zhang J, Van V, Mahmud I, Wei B, Lorenzi P, Raso M, Aparicio A, Lu Y, Frigo D, Gan B, Zhao D*. . Nature Cancer. 2025 May 13. doi: 10.1038/s43018-025-00952-z. Online ahead of print. PMID: 40360905.
Meng C, Lin K, Shi W, Teng H, DeBruine A, Wang Y, Chen F, Leo J, Zhang J, Van V, Maldonado K, Gan B, Ma L, Lu Y*, Zhao D*. . Nature Communications. 2025 May 20. doi: 10.1038/s41467-025-59381-2. PMID: 40394007.
Shi W, Wang Y, Zhao Y, Kim JJ, Li H, Meng C, Chen F, Zhang J, Mak DH, Van V, Leo J, St Croix B, Aparicio A, Zhao D*. . Science Translational Medicine. 2023 May 10; 15(695): eadf6724. doi: 10.1126/scitranslmed.adf6724. PMID: 37163614.
Li H, Wang Y, Lin K, Venkadakrishnan V, Bakht M, Shi W, Meng C, Zhang J, Tremble K, Liang X, Song J, Feng X, Van V, Deng P, Burks J, Aparicio A, Keyomarsi K, Chen J, Lu Y, Beltran H, Zhao D*. . Cancer Research. 2022. doi: 10.1158/0008-5472.CAN-22-0631. PMID: 35771632.
Our Funding
National Cancer Institute (NCI) R01 CA278889
NCI R01 CA275990
Department of Defense IDA PC230358
Prostate Cancer Foundation Challenge Award
CPRIT Recruitment Award RR190021
Pathway to Independence Award (K99/R00) CA226360
Contact Us
Phone: 713-745-5214
Email: DZhao2@MDAnderson.org