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Dr. Tran and his laboratory have been continuously funded by both the federal government (National Institutes of Health [NIH] and Department of Defense [DoD]) and foundations for over a decade. Research in the Tran Lab focuses on:

1. Pathways critical for the development, progression and maintenance of genitourinary (prostate and bladder), lung and gastrointestinal (liver and pancreas) cancers
2. Tumor cell epithelial plasticity programs such as the epithelial-mesenchymal transition (EMT) and their implications for tumorigenesis, metastasis, metabolism, treatment resistance, and radiation-induced fibrosis
3. Novel targeted agents as tumor selective radiosensitizers to increase the therapeutic ratio of clinical radiotherapy
4. The use of inducible mouse models to simulate molecularly targeted therapies for malignancies and radiation-induced late effects

Our research utilizes a variety of transgenic mouse models and non-invasive imaging as well as traditional molecular, biochemical and cell biology approaches.

View a list of publications from the Tran Lab