Lab Members
Principal Investigator
Assistant Professor
Cancer Prevention and Research Institute of Texas (CPRIT) Scholar in Cancer Research
Email: YPan4@MDAnderson.org
Dr. Yuan Pan's research program lies at the intersection of neuroscience and cancer biology. The Pan Lab, established in the Department of Symptom Research in 2022, focuses on understanding the interactions between neurons, cancer cells and chemotherapy. These efforts aim to shed light on the pathogenesis of several types of nervous system cancers and to provide potential strategies for predicting, treating and preventing these cancers and improving patient quality of life.
Dr. Pan trained with Drs. David Gutmann and Michelle Monje in cancer neuroscience, neurofibromatosis type 1 (NF1) and glial biology. Her recent work has revealed that neuronal activity synchronizes with germline Nf1 (a tumor suppressor) mutation to drive the initiation and maintenance of optic pathway glioma ().
Dr. Pan was recently named a 2024 Andrew Sabin Family Fellow in Basic/Translational Science.
Anand K. Singh, Ph.D.
Senior Research Scientist
Anand joined the Pan Lab in October 2022. He is a neuroscientist with more than 15 years of experience in preclinical drug testing and regulatory affairs. He completed his Ph.D. at CSIR¨CIndian Institute of Toxicology Research, where he and his colleagues established a new pesticide-induced mouse model of Parkinson¡¯s disease. During his postdoctoral fellowship at Linkoping University, he worked on the neurocircuitry of the affective dimension of inflammatory pain. Currently, Anand is handling multiple projects on chemotherapy drug treatment, the assessment of neurotoxic side effects, and reverse translation of a small molecule inhibitor targeting oxidative phosphorylation as an anticancer strategy.
Benjamin E. Aghoghovwia, Ph.D.
Research Scientist
Benjamin came to the Pan Lab in November 2022. He obtained his doctoral degree from the University of Otago in Dunedin, New Zealand in 2018 and completed his postdoctoral training at both Otago and the University of California, San Francisco. His Ph.D. thesis and postdoctoral research mainly explored the therapeutic efficacy of stem cells in neurological disorders of the basal ganglia, such as neonatal stroke and cerebral palsy. His interest in expanding knowledge in neuroscience led him to the Pan Lab. His career goal is to understand the mechanisms of neuron-glia interaction in neurogenetic disorders such as neurofibromatosis type 1 (NF1), which will contribute to the development of novel therapeutics, extend the frontiers of knowledge and promote patient care.
Kechen Ban, Ph.D.
Research Scientist
Kechen has been a member of the Pan Lab since March 2023. He received his doctoral degree in molecular biology from the University of Putra, Malaysia. He has more than 20 years of experience in cancer research. Currently, his main interest is to understand the neuronal regulation of nervous system cancer and glia-mediated neurological deficits.
Khalil Ali Ahmad Kasm, Ph.D.
Postdoctoral Fellow
Khalil joined the Pan Lab in July 2022. He obtained his Ph.D. in pharmacology from Shanghai Jiao Tong University in 2021. His research focuses on the field of cancer neuroscience and neuropharmacology. He has eight years of research experience in chronic pain, neuronal-glial interaction and oxidative stress, and he has published several peer-reviewed manuscripts. His career goals are to discover the mechanisms of action of novel therapies and disease-related pathogenesis by using preclinical and translational research that can substantially benefit clinical research and improve patient quality of life.
In his free time, Khalil enjoys swimming, football, hiking and cooking.
Momo K. Harris, B.S.
Senior Research Assistant
Momo joined the Pan Lab in February 2024. She earned her B.S. in biology from Brigham Young University in 2018, where she first learned lab management skills in the Evolutionary Ecology Lab with live-bearing fishes. Since graduating, she has worked with mice extensively in neuroscience and cancer biology. In the Pan Lab, she functions as the general lab manager, supervising the animal colony as a whole and lending research support to behavioral and immunohistochemistry experiments.
Momo¡¯s hobbies include crafting, playing with the Houston Concert Band, reading and listening to books and playing board games.
Chhay Hok, B.S.
Research Assistant I
Chhay earned his B.S. in Nutrition from Texas A&M University in May 2024. During his time there, he was involved in murine model research examining how maternal nutrition affects offspring metabolic and cardiovascular outcomes. That experience solidified his passion for research and shaped his desire to pursue a career in biomedical science. Chhay is excited to continue building on this foundation in the Pan Lab, where he looks forward to gaining new skills and learning from experienced scientists. His long-term goal is to pursue a graduate degree and continue doing research aimed at improving cancer treatment.
In his free time, Chhay enjoys staying active, cooking, and reading.
Alesandra Echeand¨ªa Marrero
Ph.D. Student
Alesandra was a rotating graduate student in the Pan Lab from January to March 2024. In May 2024, she joined the lab as a permanent member. She is continuing her Ph.D. studies in the neuroscience program at the MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences.
Cheng-En (Allen) Shen, M.S.
Ph.D. Student
Allen is a Ph.D. student enrolled at the MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences. He joined the Pan Lab in March 2024 as a rotation student and in May became a full-fledged member of the lab. He earned his master's degree in molecular and cellular biology from National Tsing Hua University in 2020. His research at that time delved into tumor metabolism and its implications for cancer progression. Subsequently, he became a research assistant in a neurotechnology laboratory at Academia Sinica, where he led a project to design molecular tools for precise control of neurotransmitter receptors by using optogenetics techniques. Currently, his main interest is to explore the involvement of tumor suppressors in neuron-glia/glia-glia communication, neurological function, and gliomagenesis.
Outside the lab, Allen is an animal lover, especially cats and dogs. He enjoys playing pickleball and badminton.
Sandra Alb
Undergraduate Research Volunteer
Sandra, a student at Rice University, joined the Pan Lab in August 2025 and will be with us throughout the fall semester. She is majoring in neuroscience and minoring in biochemistry. She is interested in the intersection of oncology and neuroscience, and in the clinical application of research in this domain. She intends to pursue an M.D. or M.D./Ph.D. degree after graduation and ultimately to work in neurology or neurosurgery. Her bench mentor in the Pan Lab is Allen Shen.
Outside of the lab and classroom, Sandra enjoys cycling, reading, playing the piano, and sailing. She is an avid traveler and polyglot, and she enjoys visiting her family in her home country of Romania during summers.
Nathan Chen
Undergraduate Research Volunteer
Nathan is a sophomore at Rice University. He is interested in medicine, computer science and health policy in general, and in neuroscience more specifically. A native of Iowa City, he has studied abroad twice, most recently in South Korea. In the Pan Lab, he looks forward to exploring the new (to him) field of cancer neuroscience.
Outside the lab, Nathan enjoys playing sports, reading books of all kinds and trying new things.
Elise (Sae-Eun) Cho
Undergraduate Research Volunteer
Elise joined the Pan Lab in May 2025. She is a sophomore at Rice University majoring in neuroscience and minoring in medical humanities, and she is also pursuing a certificate in Spanish. She is interested in both neuroscience and oncology, and she hopes to delve into the intersection of these interests in the Pan Lab. She plans to pursue medicine after completing her undergraduate degree.
Outside of the lab, Elise loves reading novels and writing short stories and poetry.
Melissa (Xiaoyu) Geng
Undergraduate Research Volunteer
Melissa joined the Pan Lab in May 2025. She is an undergraduate student at Rice University working towards a dual degree in neuroscience and sports medicine. She has used electrophysiology techniques to conduct research on microglial regulation of obesity, and she is more than excited to further explore the field through cancer neuroscience research at the Pan Lab. Her ultimate aim is to pursue a medical career in either neurology or neurosurgery.
As a native Houstonian, Melissa loves exploring the city¡¯s diverse food culture and trying out new restaurants and cafes with friends. In her free time, she enjoys biking, bodybuilding and binge-watching dramas on the couch.
Nayia Kyriacou
Undergraduate Research Volunteer
Nayia is an undergraduate student at Rice University, majoring in biosciences with a minor in neuroscience. Her career interests are strongly focused on cancer research, as she is passionate about contributing to scientific discoveries that can improve patient outcomes and transform treatment approaches. She plans to pursue graduate school to further develop her expertise in cancer biology and translational medicine. She has stepped away from the lab for the fall 2025 semester but plans to return to us in the spring.
Outside of academics and research, Nayia enjoys drawing, painting and acting, which allows her to express her creativity and maintain balance in life. She thrives on exploring new fields and ideas, whether through science, the arts or connecting with people from different backgrounds.
Shreya Raja
Undergraduate Research Volunteer
Shreya is a rising sophomore at Âé¶¹Ó³» in Austin, where she worked in the DIY Diagnostics Lab as part of the Freshman Research Initiative Program. Next semester, she will work with a team to design a diagnostic device, possibly for Huntington disease, to be used in low-resource situations. Her future goals including earning her Ph.D., conducting research, and becoming a professor.
In her free time, Shreya enjoys painting, listening to music, playing the guitar, and watching shows and movies. Her current preferences include cooking shows, Death Note, and Stranger Things; her all-time favorite movie is Pride and Prejudice. She is also a huge cat person.
Ella (Meishan) Zhou
Undergraduate Research Volunteer
Ella is studying neuroscience at Rice Univeristy. She is also interested in bioengineering. She hopes to pursue a career in neuropathology research.
Outside of the lab, Ella loves photography, gaming and running.
Sama A. Alnassiry, B.S.
Sama joined the Pan Lab in May 2022, shortly after earning her B.S. in biomedical sciences from Rochester Institute of Technology. Her research there focused primarily on understanding the bacteria Streptococcus Mutans K. She left the lab in April 2024 to join UT Health as a research associate.
Renae E. Bertrand, Ph.D.
Renae joined the Pan Lab as a Research Investigator in April 2023. She is now a Senior Grants and Contracts Specialist at Âé¶¹Ó³» Heath Science Center at Houston (UT Health Houston).
Aishani S. Gargapati, B.S.
Aishani joined the Pan Lab in October 2023 as a student volunteer. After graduating from Rice University in May 2024, she joined the lab full time as a Research Assistant I. She aspires to becoming a physician-scientist, providing patient-centered care and conducting cancer research, and in May 2025 she left the lab to pursue medical school at UT Tyler.
Khushboo Irshad, Ph.D.
Khushboo was a Research Scientist in the Pan Lab from 2022 to 2025. She completed her Ph.D. in biochemistry at All India Institute of Medical Sciences (AIIMS), New Delhi, India, in 2013. Her Ph.D. thesis and postdoctoral research involved the study of signaling pathways implicated in brain tumors and patient-derived primary cultures. In September 2025, she embarked on the next chapter of her research career at the University of Arizona.
Tahara Trimble, B.S.
Tahara was a Research Assistant I in the Pan Lab until she left in the fall of 2025 to begin her own business. She is a dedicated healthcare professional with a solid foundation in healthcare settings. Her strong understanding of patient care and symptom management drives a passion for research aimed at improving patient outcomes.
Mar¨ªa Monserrath Olivera Acevedo, °Õ±ð³¦²Ô´Ç±ô¨®²µ¾±³¦´Ç&²Ô²ú²õ±è;de Monterrey
Madeline N. Ansley, Rice University
Nathan T. Bui, Rice University
Rommel Caballero-Juarez, Rice University
Varsha K. Chandramouli, Rice University
Seynabou (Zaina) Diagne, Dartmouth College
Hana El-Toukhy, University of Houston
Ava S. Hamblett, Rice University
Tasneen Islam, Western University of Health Sciences - Oregon
Emilia Gibson Lopez, Tecnol¨®gico de Monterrey
Sara E. Maupin-Garcia, Rice University
Alexia Torres Mendoza, °Õ±ð³¦²Ô´Ç±ô¨®²µ¾±³¦´Ç&²Ô²ú²õ±è;de Monterrey
Samer Sharafaldin, University of Houston
Avani Shepherd, B.S., McGovern Medical School
Valeria Vega, Tecnol¨®gico de Monterrey
Jade Xu, Rice University
Elsayed (Sayed) Zaabout, MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences
Eric T. Zhang, Rice University
Shungu Zimbwa, Rice University