Krebs Laboratory
Simone Krebs, M.D.
Principal Investigator
Areas of Research
- Imaging
- Theranostics
- Targeted Therapy
- Adoptive Cell Therapy
- CAR T-cells
The primary focus of the Krebs Laboratory is the development and preclinical evaluation of imaging and theranostic agents including in conjunction with cellular engineering. Our bench-to-bedside research program includes chemistry, cellular biology, immunology, animal research and clinical translation.
Our Research
We are developing a non-invasive, safe, sensitive and specific methodology to monitor genetically altered human immune cells, called chimeric antigen receptor (CAR) T cells, after they have been transferred into patients to treat cancer. We are also investigating theranostic approaches that target established and novel markers on the tumor and/or tumor microenvironment (TME) to:
- Elucidate the localization, dynamics and underlying molecular pathways of immune-suppressive molecules in the TME
- Administer radioimmunotherapy
We are specifically investigating approaches to treat and diagnose glioma, lymphoma and other selected tumors.
Lab News
October 2025
Noor presents her first poster at the World Molecular Imaging Conference (WMIC) 2025 entitled ¡°NAM-Informed Dosimetry: Integrating Computational Phantoms with Emerging Biological Models.¡±
September 2025
Celine is appointed to serve a two-year junior leadership role with the Molecular Imaging Nanotechnology and Theranostics (MINT) interest group of the World Molecular Imaging Society (WMIS).
August 2025
Dr. Krebs was invited to speak at the MD Anderson Research Town Hall on theranostics.
July 2025
Celine Chevaleyre, Pharm.D., Ph.D., joins the lab.
June 2025
Noor Ali, Ph.D., joins the lab.
February 2025
Hamid Mirzaei, Ph.D., joins the lab.
Contact Us
Principal Investigator
Associate Professor, Nuclear Medicine and Imaging Physics
Email: SSKrebs@MDAnderson.org
Address
MD Anderson Cancer Center
Nuclear Medicine
South Campus Research Building 3
1881 East Road
Houston, TX 77054