Pan Laboratory
Hui-Lin Pan, Ph.D.
Principal Investigator
Areas of Research
- Anesthesiology
- Cancer Neuroscience
- Cardiology
- Chronic Pain
- Epigenetics
Our neuroscience research focuses on the function of voltage- and ligand-gated ion channels and synaptic plasticity in chronic pain, opioid actions, and neurogenic hypertension. Our current studies include: (1) neural circuitry and molecular mechanisms of chronic neuropathic pain caused by cancer chemotherapy, surgery, and nerve trauma; (2) signaling transduction mechanisms involved in opioid-induced hyperalgesia and analgesic tolerance; and (3) roles of the hypothalamus and sympathetic nervous system in neurogenic hypertension caused by chronic stress and clinically used medications.
Hui-Lin Pan Lab Members
Meet the teamCurrent Grant Support
From the National Institutes of Health (NIH)
- Signaling Mechanisms of Opioid-Induced Hyperalgesia and Tolerance. NIH/National Institute on Drug Abuse (R01 DA041711); 03/2017¨C07/2027, Principal Investigator (MPI: Shao-Rui Chen).
- Molecular Determinants of Synaptic Plasticity in Neuropathic Pain. NIH/National Institute of Neurological Disorders and Stroke (R01 NS101880); 08/2017¨C11/2027, Principal Investigator (MPI: Shao-Rui Chen).
- Targeting HB-EGF and trigeminal EGFR for oral cancer pain and opioid tolerance. NIH/National Institute of Dental and Craniofacial Research (R01 DE032501); 10/2022¨C09/2027, Sub-award Co-Investigator (PI: Yi Ye, New York University).
- Mechanisms of Epigenetic Plasticity in Neuropathic Pain. NIH/National Institute of Neurological Disorders and Stroke (R01 NS122241); 04/2023¨C03/2028, Principal Investigator (MPI: Shao-Rui Chen).
Life in the Lab
Contact Us
Professor, Department of Anesthesiology and Perioperative Medicine
Division of Anesthesiology, Critical Care Medicine, and Pain Medicine
Office Location
Bates-Freeman (Y6.5613)
1515 Holcombe Blvd
Houston, TX 77030
Email: huilinpan@mdanderson.org
Phone: 713-563-5838