Gorlick Laboratory
Richard Gorlick, M.D.
Principal Investigator
H. Grant Taylor, MD, W.W. Sutow, MD and Margaret P. Sullivan, MD, Distinguished Chair in Pediatrics
- Departments, Labs and Institutes
- Labs
- Gorlick Laboratory
Research Areas
- Osteosarcoma
- Targeted Therapy
- Chemotherapy
- Immunotherapy
The research in the Gorlick Lab is focused on conducting translational studies aimed at improving outcomes for children, adolescents and young adults with osteosarcoma, which is the most common primary malignant bone tumor in this patient population. Utilizing genomic and proteomic approaches, our lab identifies novel targets in osteosarcoma ripe for therapeutic intervention with the goal of developing new immunotherapies to be assessed in pre-clinical studies and clinical trials.
The Gorlick Laboratory has been a member of the National Cancer Institute-funded Pediatric Preclinical Testing Program/Consortium and Pediatric Preclinical In Vivo Testing Consortium (PIVOT) since its inception and has assessed the efficacy of more than 100 novel anti-cancer agents in osteosarcoma patient-derived xenograft (PDX) models.
Research in the Gorlick Lab has directly led to a number of osteosarcoma clinical trials within and outside of the Children¡¯s Oncology Group.