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As a type of immunotherapy, cell therapies enhance the natural abilities of immune cells, such as T cells and natural killer (NK) cells, to detect and eliminate cancer cells at a magnitude the human body could never do alone. Cancer cells can often make themselves invisible to the immune system. Therefore, to better detect cancer cells, we can genetically modify immune cells by adding certain molecules, such as a chimeric antigen receptor (CAR). Cell therapies also can be engineered to enhance their activity against target cells.

Bringing together the top minds in the field, the Institute for Cell Therapy Discovery & Innovation will lead exceptional discovery, translational and clinical research to accelerate the development of new treatments for cancer as well as autoimmune diseases, infections and other conditions. The institute aims to provide safe and effective therapies that will be available "off-the-shelf," which could improve access and lower treatment costs.

Home to the world¡¯s largest cancer clinical trials program, MD Anderson leverages its tremendous research engine to advance new cell therapy applications safely and quickly. We draw upon expertise in immunology, cancer genomics, drug development, data science and artificial intelligence to translate scientific discoveries into impactful treatments. By gaining new insights in immunology and cell engineering, the institute will fuel the creation of breakthrough therapies that can be readily adapted to address emerging needs.