5 things to know about clonal hematopoiesis
Bone marrow is the factory for our blood cells. New cells are created as old cells divide and split. During that process, a mistake can sometimes occur, and that likelihood increases as we age. These abnormalities are called gene mutations.
When abnormal cells accumulate in the bone marrow, it can be a sign of a type of blood cancer called leukemia.
But it¡¯s also possible to have mutations within the bone marrow without...
Radiation therapy, the immune system and what¡¯s ahead
Radiation therapy is often thought of as a treatment for localized cancer that hasn¡¯t spread. But when paired with other therapies, it can...
Liver regeneration: How the liver¡¯s ability to recover plays into liver cancer surgery
Did you know that the liver is the only internal organ that can regenerate? But it doesn¡¯t grow back like a salamander¡¯s tail. When a portion...
Optimizing CAR T cell therapy with bridging radiation therapy
For many patients diagnosed with certain types of B-cell lymphoma, leukemia and multiple myeloma, chimeric antigen receptor (CAR) T cell therapy offers an effective treatment option. This cellular therapy is created by extracting a patient¡¯s T cells, modifying them in a lab to identify and attack cancer cells, and returning them to the patient.
The process of creating the CAR T cells can take three to four weeks. Radiation therapy...
Peripheral neuropathy: Causes, symptoms and treatments
Many patients receive chemotherapy as part of their cancer treatment plan. These drugs have long shown benefits in extending patients¡¯ lives...
4 things to know about marginal zone lymphoma
Lymphoma is often thought of as a cancer of lymph nodes, but it's actually a cancer of the lymphocytes. Lymphocytes are white blood cells...
Antibody drug conjugates: A shift in treatment options for solid tumors
Antibody drug conjugates have existed for years, but several recent advances are helping to refine how these cancer drugs work, expanding...
Spatial omics offer a deeper look at tertiary lymphoid structures in cancer
Tertiary lymphoid structures are highly organized clusters of immune cells that form in non-lymphoid tissues. They¡¯re often found at sites...
How BTK inhibitors treat mantle cell lymphoma
B cells are an important part of the immune system. One of their jobs is to neutralize the threat from a foreign invader known as a pathogen...
LAG-3 inhibitors: A new type of immunotherapy
Immunotherapy harnesses the natural power of the immune system and enhances its response to cancer. Immune checkpoint inhibitors are the most...