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Researchers at Â鶹ӳ»­ MD Anderson Cancer Center have shown how pretreatment clonal complexity in pancreatic tumor cells leads to chemotherapy resistance, findings that could lead to better-personalized and effective combination therapies.

Tumorigenesis is an evolutionary process. ¡°A tumor is an ecosystem composed of different cell populations, and the fittest survive,¡± says Alessandro Carugo, Ph.D., research scientist...