Researchers identify enzyme involved in driving neuron differentiation
A new study from Â鶹ӳ» MD Anderson Cancer Center identified an important role for the KMT2D protein in controlling the development of brain cells necessary for motor coordination and cognitive functions.
The study, published today in Science Advances, was led by Shilpa Dhar, Ph.D., assistant professor of Gastrointestinal Medical Oncology, Jae-il Park, Ph.D., professor of Experimental Radiation Oncology, and Min...
Sugary drinks may increase risk of metastasis in advanced colorectal cancer
Preclinical study provides first direct evidence linking colorectal cancer metastasis to the glucose-fructose blend found in sugar-sweetened...
Digital twin model shows promise for predicting bone metastasis treatment response in prostate and renal cancers
A new study, published in Cancer Research, highlights the development of advanced digital twin models designed to more accurately reflect...
Novel sequencing technology links DNA and RNA to provide molecular insights into breast cancer progression
Breast cancer often starts in the epithelial cells lining the milk ducts and lobules, but there are many subtypes that make it challenging to identify the cancer’s starting point within normal tissue. Researchers led by Nicholas Navin, Ph.D., developed a new single-cell DNA and RNA sequencing technology – called wellDR-seq – to identify ancestral breast cancer cells. By studying the impact of chromosome gains or losses on gene expression...
Targeted radiation helps patients with kidney cancer delay systemic therapy 
Some patients with clear cell renal cell carcinoma (ccRCC) – the most common type of kidney cancer in adults – experience oligometastatic...
Researchers identify predictive biomarkers for oral cancer metastasis
Most oral cancers start in squamous cells lining the mouth and tongue, and frequently metastasize to the lymph nodes. To identify potential...
First-in-class pan-KRAS inhibitor shows strong antitumor activity in preclinical models
KRAS is the most commonly mutated gene in cancer, but targeting the mutant protein is notoriously difficult because current therapies work...